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HA is the main component composing human intercellular substance, vitreum joints synovia, etc. It can retain water, keep intercellular space, accommodate osmotic pressure, lubricate and further rehabilitation of cells. In its aqueous solution, a mount of carboxyl and hydroxy in its molecular, which can form hydrogen bondings in molecule and between molecules, thus making it a powerful water keeping action. It can bond water over 400 multiple. In upper consistence, HA aqueous solution has high viscoelasticity because of its molecules form complex three reticula grades. As a main component of intercellular substance, HA directly concerns the transfer of exchange of electrolyte inside and outside cells, demonstrates the filter action of physical and molecule information. Macromolecule HA can prevent cells from move, hyperplasia, disintegration and engulfment, while low olecule HA has furtherance actions.